Lactate Dehydrogenase Antibody
Rabbit mAb
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND

Application
| WB, IHC, FC, ICC, IP |
|---|---|
| Primary Accession | P00338 |
| Reactivity | Rat |
| Clonality | Monoclonal |
| Other Names | LDHA; LDH-M; LDH1; PIG19; GSD11; TRG5; Proliferation inducing gene 19; |
| Isotype | Rabbit IgG |
| Host | Rabbit |
| Calculated MW | 36689 Da |
| Dilution | WB 1:500~1:2000 IHC 1:50~1:100 ICC/IF 1:50~1:100 IP 1:50 FC 1:50 |
|---|---|
| Purification | Affinity-chromatography |
| Immunogen | A synthesized peptide derived from human Lactate Dehydrogenase |
| Description | Lactate dehydrogenase (LDH) catalyzes the interconversion of pyruvate and NADH to lactate and NAD+. When the oxygen supply is too low for mitochondrial ATP production, this reaction recycles NADH generated in glycolysis to NAD+, which reenters glycolysis. The major form of LDH found in muscle cells is the A (LDHA) isozyme. |
| Storage Condition and Buffer | Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Store at +4°C short term. Store at -20°C long term. Avoid freeze / thaw cycle. |
| Name | LDHA (HGNC:6535) |
|---|---|
| Function | Interconverts simultaneously and stereospecifically pyruvate and lactate with concomitant interconversion of NADH and NAD(+). |
| Cellular Location | Cytoplasm. |
| Tissue Location | Predominantly expressed in anaerobic tissues such as skeletal muscle and liver. |

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